Author/Authors :
Bakhtiari، Sedigheh نويسنده Department of Oral medicine,Shahid
Beheshti University of Medical Sciences,Tehran,Iran , , Azimi، Somayyeh نويسنده Department of Oral medicine,Shahid
Beheshti University of Medical Sciences,Tehran,Iran , , Mehdipour، Masoumeh نويسنده Faculty of Dentistry,Department of Oral Medicine,Shahid Beheshti University of Medical Sciences,Tehran,Iran , , Amini، Somayyeh نويسنده Tehran,Iran , , Elmi، Zahra نويسنده Department of Oral medicine,Shahid Beheshti University of Medical Sciences,Tehran,Iran , , Namazi، Zahra نويسنده Department of Dental Materials,Tehran University of Medical Sciences,Tehran,Iran ,
Abstract :
Background and aims. Cigarette smoke can induce oral cancer by its
free radicals and oxidative damage. Salivary antioxidants system is
believed to have an important role in defense mechanisms against
oxidative stress. This study was compared total antioxidant capacity
(TAoC) of saliva in smokers and nonsmokers.Materials and methods. In
this crosssectional study, 30 male smokers with mean age of 45.23 years
and 30 nonsmokers with mean age of 45.30 years participated.
Unstimulated whole saliva sles were collected in the morning in two
groups by spitting method. TAoC of saliva was measured with the special
kit in two groups at the same time. Statistical analysis was performed
by covariance test.Results. The mean salivary TAoC in nonsmokers
(0.741±0.123 U/ml) was higher than that in smokers (0.529±0.167 U/ml).
This difference was statistically significant (P<0.001).Conclusion.
Smoking can alter salivary antioxidant capacity.
