Author/Authors :
Varamini، Sanam نويسنده School of Pharmacy, International Branch of Shiraz University of Medical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. , , Sakhteman، Amirhossein نويسنده Department of Medicinal Chemistry, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. , , Yousefi، Gholamhosein نويسنده Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. , , Sepehri، Masood نويسنده Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. , , Faridi، Pouya نويسنده Department of Traditional Pharmacy, Shiraz Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran , , Zarshenas، Mohammad M. نويسنده Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran ,
Abstract :
Commiphora mukul (Hook. ex Stocks) Engl. (from the family Burseraceae) is well known for the clinical applications of its gummy compositions. The gum possesses many pharmacological activities such as antiseptic, astringent, anti-inflammatory, and antimicrobial activities. To outline the chemical compositions of this medicament, current study has evaluated the essential oil extracted from different C. mukul gum samples found in medicinal plant markets in Iran. Five different samples were purchased from medicinal plant market in Shiraz and were coarsely milled and subjected to a Clevenger-based hydrodistillation. Subsequently GC/MS analysis was performed for each sample by means of a gas chromatograph (Agilent Technologies 7890) coupled with a mass detector (Agilent Technologies model 5975C). Identification of the constituents was performed based on a comparison of their mass spectra with Willey (nl7) and Adams libraries spectra, as well as with those reported in literature. The yield of extracted colorless but turbid essential oil from those samples was calculated at the range of 0.5-1% (V/W). Totally, 41 different components were identified for those collected samples. The major constituent (more than 5%) found in all samples was alpha-cadinol (7.25-14.49%). Results of the current procedure can be considered as a reference for the analysis and control of different C. mukul samples in market.
