Author/Authors :
Azadforouz، Sanaz نويسنده Babol University of Medical Sciences, Babol, IR
Iran , , Shabani، Amir نويسنده Departments of Psychiatry, Mental Health Research Center, Tehran University of Medical Sciences, Tehran, Iran , , Nohesara، Shabnam نويسنده , , Ahmadzad Asl، Masoud نويسنده Department of Psychiatry, Qazvin University of Medical Sciences, Qazvin, IR Iran Ahmadzad Asl, Masoud
Abstract :
Background Medication treatment compliance among bipolar patients
is quite widespread. Objectives Treatment compliance depends on multiple
factors. The aim of this study was to evaluate the predicting factors of
noncompliance in patients with bipolar I disorder admitted to an Iranian
hospital during a six-month follow up period. Materials and Methods This
cross-sectional study included 47 bipolar I disorder subjects who were
admitted to the Iran psychiatric hospital and that were chosen using a
non-randomized convenient sampling model. The patients were assessed at
baseline, and at two and six months after admission. For evaluating the
patients, we used the medication possession ratio (MPR), the drug
attitude inventory (DIA-10), the young mania rating scale (Y-MRS) and
the scale for the assessment of positive symptoms (SAPS). The data were
analyzed using a general linear model by SPSS 16 software. Results The
repeated measures analysis revealed that medication compliance increased
successively (P = 0.045), and age, gender and symptom severity did not
alter the pattern. Conclusions There is an increasing pattern in
treatment compliance in bipolar I disorder patients, regardless of the
known predicting factors for nonadherence.
