Author/Authors :
Taghi Akhi، Mohammad نويسنده Department of Bacteriology and Virology, Tabriz University of Medical Sciences, Tabriz, IR Iran , , Esmailkhani، Aylin نويسنده Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran , , Sadeghi، AylinJavid نويسنده Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran , , Niknafs، Behrooz نويسنده Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz , , Farzadi، Laya نويسنده Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran , , Akhi، Aydin نويسنده Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran , , Najafi Nasab، Elmira نويسنده Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran ,
Abstract :
Background: Infertility is one of the major social issues. Due to the asymptomatic cervical
infection associated with Staphylococcus aureus (S. aureus), the majority of patients
remain undiagnosed. The present study intended to assess the frequency of S. aureus
isolated from infertile women’s endocervix in northwest Iran.
Materials and Methods: In a descriptive cross sectional study, specimens were randomly
collected during vagina examination using a sterile speculum and swabbing. After performance
of antibiotic susceptibility testing, polymerase chain reaction (PCR) was used to identify
methicillin-resistance S. aureus (MRSA) and toxic shock syndrome toxin-1 (TSST-1).
Results: About 26 (26%) and 9 (9%) women’s urogenital tracts were colonized by S.
aureus and Candida spp., respectively, of which three (11.5%) patients were infected with
fungi and S. aureus, simultaneously. Antibiotic susceptibility results showed high activity
of vancomycin and co-trimoxazole on isolates. Regarding PCR results, mecA sequences
were detected in 7 (26.9%) strains, whilst the tst gene encoding TSST-1 was not detected
in any of clinical strains.
Conclusion: The prevalence of S. aureus was very high in infertile women. Therefore, it
demands all patients undergoing infertility treatment to be investigated thoroughly for this
type of infection.
