Author/Authors :
Zakerinasab، Batol نويسنده Department of Chemistry, College of Sciences, University of Birjand, Birjand 97175-615, Iran. , , Nasseri، Mohammad Ali نويسنده , , Kamali، Fateme نويسنده Department of Chemistry, College of Sciences, University of Birjand, P.O. BOX 97175-615, Birjand, Iran Kamali, Fateme
Abstract :
Quinolines, an important class of potentially bioactive compounds, have been synthesized by treatment of O-aminoarylketones and carbonyl compounds utilizing niobium-(V) chloride /-polyethylenglycole(NbCl5.PEG) and niobium(V) chloride (NbCl5) as available and inexpensive catalysts. The quinoline derivatives were prepared in glycerol, as an excellent solvent in terms of environmental impact, with high yields (76-98%) and short reaction times (15-90 min).