Author/Authors :
Moein، Elham نويسنده Department of Traditional Pharmacy, Traditional Medicine
and Materia Medica Research Center, School of Traditional Medicine,
Shahid Beheshti University of Medical Sciences, Tehran, IR
Iran , , Hajimehdipoor، Homa نويسنده Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , , Hamzeloo Moghadam، Maryam نويسنده Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , , Choopani، Rasool نويسنده Department of Traditional Medicine, School of Traditional
Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR
Iran , , Toliyat، Tayebeh نويسنده Department of Pharmaceutics, Faculty of Pharmacy, Tehran
University of Medical Sciences, Tehran, IR Iran ,
Abstract :
In Iranian traditional medicine (ITM), purgation is a simple and
effective way of removing waste humors from the body. Purgation not only
increases peristaltic movements in the gastrointestinal system but also
relieves many symptoms that arise due to the retention of waste humors
in the body’s organs. The aim of the present study is to introduce one
of the most important Aloe-based purgative medications used in ITM:
Ayarij-e-Faiqra. The main Iranian medical and pharmaceutical text books,
composed between the 9th and 19th centuries, were searched for key words
related to Ayarij and Faiqra. All references to and formulations of
Ayarij-e-Faiqra were reviewed. Then, scientific databases, including Web
of Knowledge, Science Direct, PubMed, and Google Scholar were searched
for references to the biological effects of the plants used in
Ayarij-e-Faiqra formulations. Ayarij is the common name for medicines
that contain a purgative agent as the main constituent. Other
ingredients are often added to improve efficacy and reduce side effects,
or to allow the medicine to function as a delivering agent. Aloe is the
main constituent of Ayarij-e-Faiqra. It has a wide range of indications
and an important role in balancing the body’s humors in ITM. It can be
used, therefore, in the treatment of various diseases. The prescriptions
given differ across the manuscripts studied, with some formulations
having been used more often, although the instructions for
administration and dosage tend to differ. In both ITM and modern
medicine, Ayarij-e-Faiqra is a powerful purgative medicine because Aloe
spp. dried juice is the main ingredient. This juice has been used with
other components to increase the efficacy of the medicine and to reduce
the adverse effects associated with Ayarij-e-Faiqra. In ITM, purgative
medicine expels and eliminates waste humors from body systems. In modern
medicine, most studies focus on the polysaccharide constituent of Aloe
spp. gel (not the juice), and although data about the modifying effects
of each separate ingredient in Ayarij-e-Faiqra can be found, more
studies are required that analyze all the ingredients in Aloe spp. dried
juice in order to give a complete medical profile for
Ayarij-e-Faiqra.
