Successful Treatment of Multiorgan Toxicity Induced by Explosive Agent With Repeated Hemodialysis: A Case Report

Acute poisoning by oral ingestion of mixed hazardous materials can lead to multiorgan toxicity and may represent a special challenge in clinical management, in particular if little is known about the effects of the involved agents. This is especially true when industrial chemical substances have been swallowed, as a huge variety of toxic substances must be taken into account. This case report describes the management of this potentially life-threatening situation in a 21-year-old man with multiorgan system failure, who developed gastrointestinal bleeding, anemia, renal dysfunction, altered visual acuity, seizure, jaundice, and ascites due to multiorgan toxicity. This patient was successfully treated with repeated hemodialysis, and survived. He was discharged from the hospital with an acceptable level of morbidity. In cases of oral-based multiple hazardous substance toxicity without a specific antidote, hemodialysis seems to be the best treatment. The problems created by multiorgan toxicity and the issues involved in the decision-making process are discussed in the management of this extraordinarily overwhelming complication.