Author/Authors :
SARKARI، Bahador نويسنده Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran SARKARI, Bahador , FATEMI ESFEDAN، Asieh نويسنده Dept. of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran FATEMI ESFEDAN, Asieh , MOSHFE، Abdolali نويسنده Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran MOSHFE, Abdolali , ABDOLAHI KHABISI، Samaneh نويسنده Dept. of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ABDOLAHI KHABISI, Samaneh , SAVARDASHTAKI، Amir نويسنده Dept. of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran SAVARDASHTAKI, Amir , Hosseini Shirazi، Farshad نويسنده , , SHAHBAZI، Ardavan نويسنده Dept. of Surgery, Shahid Beheshti Hospital, Yasuj, Iran SHAHBAZI, Ardavan
Abstract :
Spleen is an unusual location for hydatid cyst. Here we report a case of primary splenic hydatid cyst in a 41-yr-old Iranian woman from Yasuj, southwest of Iran. The patient had been admitted to Shahid Beheshti Hospital because of abdominal pain. Abdominal sonography revealed a hypoechoic lesion of 150 X 130 mm in the spleen, suggestive of hydatid cyst. Splenectomy was performed for the patient and surgical interventions revealed a hydatid cyst occupying most of splenic parenchyma. She was discharged on the 5 day of her operation. Postoperative diagnosis and confirmation of hydatid cyst was done by histopathological, molecular and serological approaches. Histopathological evaluation revealed the classical laminated layer of hydatid cyst. DNA was extracted from a part of cyst and PCR amplified. Sequencing and analysis of PCR product revealed that the isolate has the most similarity with G1 strain of Echinococcus granulosus. Patient’s serum was positive for IgG anti-hydatid cyst antibodies, using antigen-B ELISA.
