Author/Authors :
Najafi، Faezeh نويسنده Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Najafi, Faezeh , Rezaie، Sasan نويسنده Department of Medical Mycology and Parasitology, School of Public Health and Institute of Public Health Research,Tehran, IR Iran , , KIA، Eshrat Beigom نويسنده Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran KIA, Eshrat Beigom , Mahmoudi، Mahmoud نويسنده , , MOHEBALI، Mehdi نويسنده Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran MOHEBALI, Mehdi , Gharagozlou، Mohammad Javad نويسنده Tehran University, Tehran, Iran Gharagozlou, Mohammad Javad , ROKNI، Mohammad Bagher نويسنده Dept. of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Infectious Diseases, AJA University of Medical Sciences, Tehran, Iran ROKNI, Mohammad Bagher , Mowlavi، Gholamreza نويسنده Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran. Mowlavi, Gholamreza
Abstract :
Background: Fascioliasis is a zoonotic disease caused by the liver fluke Fasciola hepatica. Drug resistance, high costs of treatment and economic losses in meat production have emerged the need of alternative control measures into consideration. The aim of this study was to evaluate the in vitro ovicidal activity of Paecilomyces lilacinus fungus on F. hepatica eggs.
Methods: P. lilacinus isolated from the soil of natural environment was challenged on F. hepatica eggs to observe the bio control effect of nematophagous fungi on trematode helminth eggs. The study was conducted in Tehran University of Medical Sciences, in 2015. Within 21 d of experiment, destructive effects exhibited on the eggshells were investigated using optical and Scanning Electron Microscopy.
Results: The effective role of P. lilacinus on damaging the eggs of F. hepatica was noticed.
Conclusion: This finding is promising for advantageous use of nematophagus fungi as a natural constituent in hyper endemic areas for certain helminthic infections like fascioliasis with diverse kinds of herbivores as egg passer hosts.
