Author/Authors :
Mohammadi، Sepideh نويسنده Department of Microbiology, Islamic Azad University of Pharmaceutical Sciences Branch, Tehran, Iran , , Mahboubi، Arash نويسنده Department of Pharmaceutics, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Gorgian Mohammadi، Masumeh نويسنده Dept. of Clinical Biochemistry, Tabriz University of Medical Sciences, Tabriz, Iran , , Hedayati، Mehdi نويسنده Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , , Jalili، Arsalan نويسنده Department of Biology School of Basic Science, Islamic Azad University, East Tehran Branch, Tehran, Iran ,
Abstract :
Spurge family is a large family of plants that contains more than 300 genera and 800 species of which 5 genera and 72 species are native to Iran. This important family of plants can be used in various disease treatments such as cancer, arthritis, asthma, bacterial infections, and neuralgia. This study investigated the anticancer effects of the alcoholic extract of Euphorbia condylocarpa whose native Iranian Kurdish name is “Shoalehkolah”. In this study, the cytotoxicity of the methyl extracts of Euphorbia was performed on AGS gastric cancer cell lines using the MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) assay. The cytotoxicity of the methyl extract of Euphorbia condylocarpa with dilutions of 10, 20, 100, and 200 μg/mL was considered. The obtained data showed that the greatest effect was related to the dilution of 200 μg/mL. The findings suggest that the methyl extract of this plant can be considered for its anticancer effects.
