Title of article :
Folliculotropic Mycosis Fungoides with Comedonal-like Appearances
Author/Authors :
Nikoo، Azita نويسنده , , Rahbar ، Mahtab نويسنده Department of Pathology, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. ,
Issue Information :
ماهنامه با شماره پیاپی 0 سال 2016
Abstract :
Folliculotropic mycosis fungoides (FMF) is a variant of mycosis
fungoides characterized by the presence of folliculotropic atypical
Tcells infiltrates, often with sparing of the epidermis and preferential
involvement of the head and neck. Since the original designation of
folliculotropic mycosisfungoides (FMF) is a distinct entity, there has
been an increasing appreciation of the broad clinical and histopathology
spectrum, which can present in this disease. In July 2013, a 37-year-old
male from Tehran (Iran) who had complained of 9 months of progressive
erythematous follicular patches and plaques on the trunk and comedones
and acne like lesions on his forehead has been referred to us. The
histopathology study showed perifollicular and intrafollicular lymphoid
cells infiltration predominantly. There was no histopathology evidence
of dermal mucin deposit (PAS negative) and alopeciaor syringotropism T
cell infiltration. The immunohistochemical analysis was positive for CD3
and D4. The patients received different treatments based on the stage of
their disease. FMF should be considered in patients who present with
alopecia, acne like lesions, cysts and comedones in older ages with a
spectrum of histologic changes. We emphasize for any time it should be
under-recognized.
Journal title :
Iranian Red Crescent Medical Journal
Journal title :
Iranian Red Crescent Medical Journal