Author/Authors :
Mokhtari، Vida نويسنده Department of Molecular Cytogenetics, Research and Clinical Center for Infertility, University of Medical Sciences, Yazd, Iran , , Afsharian، Parvaneh نويسنده Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine,ACECR, Tehran, Iran , , Shahhoseini، Maryam نويسنده Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran , , Kalantar، Seyed Mehdi نويسنده , , Moini، Ashraf نويسنده ,
Abstract :
N-acetyl cysteine (NAC), as a nutritional supplement, is a greatly applied antioxidant in
vivo and in vitro. NAC is a precursor of L-cysteine that results in glutathione elevation
biosynthesis. It acts directly as a scavenger of free radicals, especially oxygen radicals.
NAC is a powerful antioxidant. It is also recommended as a potential treatment option for
different disorders resulted from generation of free oxygen radicals. Additionally, it is a
protected and endured mucolytic drug that mellows tenacious mucous discharges. It has
been used for treatment of various diseases in a direct action or in a combination with
some other medications. This paper presents a review on various applications of NAC in
treatment of several diseases.