Title of article :
Seagrass-mediated silver nanoparticles synthesis by Enhalus acoroides and its a-glucosidase inhibitory activity from the Gulf of Mannar
Author/Authors :
Senthilkumar، P. نويسنده , , Ranjith Santhosh Kumar، D. S. نويسنده , , Sudhagar، B. نويسنده , , Vanthana، M. نويسنده , , Hajistha Parveen، M. نويسنده , , Sarathkumar، S. نويسنده , , Cheriyan Thomas، Jeslin نويسنده , , Sandhiya Mary، A. نويسنده , , Kannan، Chandramouleeswaran نويسنده ,
Issue Information :
فصلنامه با شماره پیاپی سال 2016
Abstract :
Enhalus acoroides (Linnaeus f.) Royle belongs
to the Family: Hydrocharitaceae is an abundantly growing
seagrass in coastal areas of Gulf of Mannar. Sea grasses
contain very good potent therapeutic properties for challenging
diseases. The current investigation is to green
synthesis Ag-NPs from Enhalus acoroides and characterize
silver nanoparticles (Ag-NPs) and evaluated a-glucosidase
inhibition activity. Furthermore, the characterization of the
same using ultraviolet–visible spectroscopy (UV–Vis),
Fourier transform infrared (FT-IR) spectroscopy, X-ray
diffraction (XRD), energy dispersive X-ray (EDX), and
followed by Transmission Electron Microscopy (TEM).
Surface Plasmon resonance exhibited the development of
Ag-NPs in UV–Visible spectra at 419 nm. The FTIR
examination was done to find and read the moiety
accountable aimed at the bioconversion of silver ions. The
crystalline form was observed in the XRD examination.
The synthesized Ag-NPs were polydispersed spherical Ag-
NPs as confirmed by EDAX and stabilized in the solution
with the spherical shapes further confirmed by TEM
analysis designate in the reading of 2–100 nm. The findings
of the study shown that Ag-NPs of promisingly proved
have strong a-glucosidase inhibitory activity by which Ag-
NPs with an IC50 47 lg/ml. This current research report is
first to account on the green synthesis of silver nanoparticles
from seagrass E. acoroides, because there is no literature
survey and investigations on Enhalus acoroides.
Hence, we suggest that Ag-NPs synthesized from E. acoroides might be a significant resource of a-glucosidase
inhibitors preparation that may benefit diabetes treatment
Keywords :
Seagrass , Enhalus acoroides , Ag-NPs , Gulf of Mannar , a-glucosidase activity
Journal title :
Journal of Nanostructure in Chemistry(JNSC)
Journal title :
Journal of Nanostructure in Chemistry(JNSC)