EFFECTIVENESS OF VITAMIN C IN PREVENTING PRE-LABOUR RUPTURE OF CHORIO-AMNIOTIC MEMBRANES IN PREGNANCY IN WOMEN HAVING HISTORY OF PROM IN PREVIOUS PREGNANCIES

Objective: To determine the effectiveness of vitamin C supplementation in preventing pre-labour rupture of chorio-amniotic membranes (PROM) in pregnancy in women having history of PROM in previous pregnancies. Methodology: This descriptive study was carried out in Department of Obstetrics and Gynaecology, Khyber Teaching Hospital, Peshawar from August 2013 to January 2014. Cases with history of PROM in previous pregnancies were included in this study. Vitamin C supplementation in preventing PROM was used in these patients. All pregnant patients presented from 22 to 28 weeks gestation received a daily dose of Vitamin C 500mg. PROM at the end of pregnancy was noted. Results: Out of 133 patients who received Vitamin C, 98 (74%) didn’t experienced PROM and 35 (26%) had PROM, showing the effectiveness of Vitamin C in preventing PROM which is effective in 74%. Conclusion: In our study Vitamin C was proved to be helpful in preventing PROM and it is suggested that patients with previous history of PROM should be given vitamin C supplementation.