Primary Splenic Hodgkin Lymphoma Presenting with Chronic Pruritus

Hodgkin Lymphoma is an uncommon B-cell lymphoma which accounts for 11.5% of all lymphomas. The majority of patients present with lymphadenopathies, and only one-third of patients are referred with fever, night sweats, weight loss and chronic pruritus. The most common extranodal sites involved in Hodgkin lymphoma are spleen, lung, liver and bone marrow.1 Spleen is the most frequent organ in abdomen which is involved in Hodgkin lymphoma,2 and sometimes it may be the only abdominal organ involved.3 But only splenic involvement without lymphadenopathies is very rare as the presenting feature of Hodgkin lymphoma. In a study of 184 cases of lymphoma in Japan, only 1.09% were involved by Hodgkin lymphoma.4