Synthesis of dihydropyrido[2,3-d]pyrimidine derivatives in the presence of sulfonic acid functionalized SBA-15 and the study of their antimicrobial activities

Abstract. SBA-Pr-SO3H was used as a green and recyclable catalyst for the synthesis of dihydropyrdo[2,3-d]pyrimidine derivatives by a three component one-pot reaction between 6-amino-1,3-dimethyl uracil, aromatic aldehydes and 1,3-dicarbonyl compounds under re ux conditions. Some of the synthesized dihydropyrido[2,3-d]pyrimidines showed antimicrobial activity against some fungi and gram positive and negative bacteria.