NANO SBCL5.SIO2: AN EFFICIENT AND HETEROGENEOUS CATALYST FOR SYNTHESIS OF 3, 4-DIHYDROPYRIMIDIN- 2(1H)-ONE (THIONE) DERIVATIVES UNDER SOLVENT-FREE CONDITIONS (RESEARCH NOTE)

Abstract. In this study, a green approach is reported for ecient and rapid synthesis of biologically active substituted 3,4-dihydropyrimidin-2(1H)-one(thione) derivatives using nano SbCl5.SiO2 as a heterogeneous catalyst under solvent-free conditions. The catalyst is characterized by FT-IR, XRD, SEM, TEM and TG-DTG analysis. Compared to the classical reactions, this method consistently has the advantages of excellent yields, simple operation, short reaction time, eco-friendly and avoidance of the use of organic solvents.