Title of article
The synthesis of 1,2-ethanediylbis(triphenylphosphonium) ditribromide as a new brominating agent in the presence of solvents and under solvent-free conditions
Author/Authors
Salmasi, Reihaneh Department of Chemistry - Faculty of Science - Ferdowsi University of Mashhad, Mashhad, Islamic Republic of Iran , Gholizadeh, Mostafa Department of Chemistry - Faculty of Science - Ferdowsi University of Mashhad, Mashhad, Islamic Republic of Iran , Salimi, Alireza Department of Chemistry - Faculty of Science - Ferdowsi University of Mashhad, Mashhad, Islamic Republic of Iran , Garrison, Jered C Department of Pharmaceutical Sciences - University of Nebraska Medical Center, Omaha, USA
Pages
10
From page
2019
To page
2028
Abstract
1,2-Ethanediylbis(triphenylphosphonium) ditribromide was quantitatively prepared and used for the bromination of anilines and phenols in the presence of a mixed solvent system (DCM/MeOH 2:1) and also under solvent-free conditions. This new ionic liquid has advantages over similar brominating agents in terms of short reaction time, simple workup, regioselectivity and high yields. Single-crystal X-ray analysis of title salt revealed that the bistriphenylphosphonium cation is organized around an inversion center located at the center of the –CH2–CH2– bridge and the two triphenylphosphine segments are anti with respect to one another. All the tribromide anions adopt a linear geometry with different Br–Br–Br bond angles for each anion.
Keywords
Bromination , Regioselectivity , Crystal structure , Nucleophilic substitutions , Solvent-free
Journal title
Astroparticle Physics
Serial Year
2016
Record number
2406735
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