Author/Authors :
Esmaili Mohammad Ali نويسنده , Nazel Khosroshahi Behzad نويسنده Emam Reza Hospital, Hamadan University of Medical Sciences, Hamadan, Iran ; Blood transfusion research center, High institute for research and Education in Transfusion Medicine, Tehran, Iran. Nazel Khosroshahi Behzad , Razjou Farhad نويسنده Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran , Amini Ali نويسنده Department of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran. , Namjoo Soodeh نويسنده Department of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran , Beigi Peyman نويسنده Faculty of Allied Medicine, Alborz University of Medical Sciences, Alborz, Iran , Rezvani Mohammad Reza نويسنده Department of Hematology, Faculty of Allied Medicine, Iran University of Medical Science, Tehran, Iran
Abstract :
Platelet components (PCs) have widespread applications in clinical cases. Since PCs store in room temperature (between 20-24°C), they are susceptible to bacterial contamination. There are varied approaches for identifying bacterial contamination in PCs. These methods categorized into two groups: Firstly, culture based methods and secondly, non-culture based methods. Both of them have a couple of merits and demerits. BacT/ALERT is a culture-based technique, which has been approved by the food and drug administration. Although sensitivity and specificity of this method could be debatable and is not universal. This method is considered as gold standard contemporary method and it is far more dependable and superb in comparison with the contamination detection methods. It is assumed that, application of rapid methods play an important role in detection of bacterial contamination in the future. Accordingly, this study aimed to represent a summary of each method, which was used for bacterial contamination detection in PCs with detailed assessment of culture-based methods, specifically BacT/ALERT.
