Author/Authors :
SABERI ALIA نويسنده , Andalib Sasan نويسنده Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz , Yousefzadeh Chabok Shahrokh نويسنده Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, IR Iran Yousefzadeh Chabok Shahrokh , Hatamian Hamidreza نويسنده Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, IR Iran , Behzadnia Hamid نويسنده Department of Neurosurgery, Poursina Hospital, Guilan University of Medical Sciences, Rasht, IR Iran , Roudbary Seyed-Ali نويسنده Neurologist, Associated Professor, Neurology Department of Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran , Bakhshayesh-Eghbali Babak نويسنده Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran , Ghayeghran Amirreza نويسنده Assistant Professor, Neurology Department of Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran , Emamhadi Mohamadreza نويسنده Brachial Plexus and Peripheral Nerve Injury Center, Guilan University of Medical Science, Rasht, Iran
Abstract :
Background: Multiple Sclerosis (MS) is a debilitating disease of the central nervous system. Usually, long-term MS medications are injected intramuscularly or subcutaneously, making them intolerable for many MS patients.
Objectives: In the present study, the rate and the causes of non-adherence to MS disease-modifying drugs (DMDs) were assessed in patients with MS.
Materials and Methods: Two hundred and three MS patients of Guilan MS Society were interviewed demographic and clinical data of the patients were collected.
Results: Among the 203 patients, 73.9% were female. The mean±SD age of the patients was 32.47±9.15. Non-adherence to DMDs was due to side effects (21.7%) and requests of the families (21.7%) or ineffectiveness (17.4%). Significant association was seen between the non-adherence to DMDs and gender (p=0.015) and relapses (p=0.021).
Conclusion: The evidence from the present study suggests that there is a high rate of non-adherence to DMDs in MS patients in Guilan.
