Author/Authors :
Fallahi Babak نويسنده Associate Professor, Department of Nuclear Medicine, School of Medicine, Shariati/Nuclear medicine, Tehran University of Medical Sciences. Tehran, Ira , Emami-Ardekani Alireza نويسنده Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, , Ranji Amjad Mina نويسنده Research Institute for Nuclear Medicine, Shariati
Hospital, Tehran University of Medical Sciences, Tehran,
Iran , Abbasi Mehrshad نويسنده Department of Nuclear Medicine, Vali-Asr Hospital, Tehran
University of Medical Sciences, Tehran, Iran , Farzanehfar Saeed نويسنده Department of Nuclear Medicine, Vali-Asr Hospital, Tehran
University of Medical Sciences, Tehran, Iran , Izadyar Sina نويسنده Imam Khomeini Medical Center, Tehran, Iran Izadyar Sina , Fard Esfehani Armaghan نويسنده Research Center for Nuclear Medicine, Shariati Hospital
Tehran University of Medical Sciences, Tehran, Iran , Esmaeli Javad نويسنده Research Center for Nuclear Medicine, Valiasr Hospital,
Tehran University of Medical Sciences, Tehran, Iran , Akhzari Fariba نويسنده Research Center for Nuclear Medicine, Sina Hospital,
Tehran University of Medical Sciences, Tehran, Iran , Geramifar Parham نويسنده Research Center for Nuclear Medicine, Shariati Hospital
Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Background Because of the increasing prevalence of both ischemic
heart diseases and vitamin D deficiency and also due to recent evidences
on association between these two phenomena, it is vital to clarify the
association of ischemic heart disease with vitamin D deficiency and low
bone mass. Objectives The aim of the present study was to assess the
relationship between low serum vitamin D and low bone mass measured by
dual-energy X-ray absorptiometry (DEXA) with ischemic heart disease
assessed by the functional radionuclide myocardial perfusion imaging
(MPI). Patients and Methods In this cross-sectional study, 204
consecutive patients aged older than 50 years who were candidates for
MPI were included. Blood sample was extracted to measure the level of
serum 25-OH vitamin D using a special kit (IDS kit). Then, the patients
were assessed by MPI. Within a month of myocardial perfusion scanning,
subjects underwent bone mineral density (BMD) measurements by DEXA
method. Results There was no significant difference in serum level of
vitamin D between patients with normal and those with abnormal MPI
results. In addition, no significant correlation was detected between
BMD and myocardial ischemia. Conclusion Coronary atherosclerosis may not
be associated with the severity of low bone mass or level of vitamin D
adequacy.
