Title of article :
Comparing the Effects of Acupuncture and Pharmacologic Therapies on Delayed
Gastric Emptying: A Prospective, Block-Randomized, Single-Blinded, Parallel
Clinical Trial
Author/Authors :
Hajiesmaeili Mohammad Reza نويسنده Anesthesiology and Critical Care Department, Tehran University of Medical Sciences and Health Services, Tehran, Iran , Dabbagh Ali نويسنده , Rahimi Bashar Farshid نويسنده Department of Anesthesiology, School of Medicine, Hamadan University of Medical Sciences , Vahedian-Azimi Amir نويسنده Behavioral Sciences Research Center and Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran , Sedaghat Alireza نويسنده Assistant Professor, Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Sedaghat Alireza , Seifi Shahram نويسنده Assistant Professor, Department of Anesthesiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran. Seifi Shahram , Tahmasebi Reza نويسنده English Department,Islamic Azad University, Torbat-e Heydarieh Branch,Torbat-e Heydarieh,Iran , Khoshraftar Ebrahimi نويسنده Department of Anesthesiology and Critical Care, School of
Medicine, Hamadan University of Medical Sciences, Hamadan, IR
Iran , Forooghirad Hosna نويسنده Clinical Research Development Center of Loghman Hakim
Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR
Iran
Abstract :
Background Nutritional therapy in the forms of parenteral or
enteral nutrition is an important factor of care and appears to
positively impact the clinical outcomes of critically ill patients.
Objectives This study aimed to compare the effects of acupuncture and
prokinetic drugs on delayed gastric emptying (DGE) in intensive care
unit patients. Methods In a prospective, block-randomized,
single-blinded, parallel group trial, 60 fully sedated, mechanically
ventilated surgical patients were enrolled in two groups with 30
patients in each group in Besat hospital in Hamadan, Iran from February
2011 to October 2012. Patients in the drug treatment group received 10
mg of IV metoclopramide every eight hours. For patients with whom
persistent DGE was seen, 500 mg of IV erythromycin every 24 hours was
added. Patients in the acupuncture group received bilateral prolonged
intermittent transcutaneous electrical acupoint stimulation of
acupuncture point Neiguan. The intervention was performed for six
consecutive days or until the cessation of gradual residual volume.
Results A demographic analysis of the participants revealed no
significant differences between groups (P > 0.05). Although the
results of the RANOVA model for DGE did not show a significant time
trend (P > 0.05) in both acupuncture and drug groups, comparing
means of the both acupuncture and drug groups in all the time points
after the intervention were significant (P = 0.024): 711.83 ± 193.28 vs.
755.00 ± 166.79 (P = 0.358), 564.17 ± 672.35 vs. 628.50 ± 176.77 (P =
0.614), 324.00 ± 146.49 vs. 472.00 ± 188.47 (P < 0.001), 209.00 ±
136.34 vs. 340.00 ± 211.89 (P < 0.006), 152.67 ± 118.93l vs.
276.17 ± 202.43 (P < 0.006), and 119.67 ± 101.59 vs. 225.67 ±
184.22 (P < 0.008) from the first to last steps, respectively.
Conclusions Although neither acupuncture nor the drug interventions had
significant effects on the improvement and obviation of DGE, the
acupuncture had greater effects than prokinetic drugs on the reduction
of DGE.
