Title of article
Seroprevalence of Hepatitis A Virus among Healthy Individuals in Birjand, Eastern Region of Iran
Author/Authors
Fereidouni Mohammad Saeid نويسنده Aquatic Animal Health Unit, School of Veterinary Medicine, Shiraz University, Shiraz, Iran, Po Box 71345-173. , Ziaee Masood نويسنده Department of Internal Medicine, Hepatitis Research Center, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, IR Iran , Mahavar Neda نويسنده Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran
Pages
4
From page
1
To page
4
Abstract
[Background]Hepatitis A virus (HAV) is an epidemiological important infectious agent in the world. HAV incidence can be controlled by cognizance of the geographic distribution pattern.[Objectives]The aim of this study was to evaluate the frequency of HAV infection in Birjand.[Methods]A total of 496 healthy individuals (mean age: 39.34 ± 15.47, range: 15 - 70 years, M/F ratio: 0.68) were randomly enrolled in this cross-sectional study. Demographic data were collected and the presence of anti-HAV total antibody was determined by the enzyme linked immunosorbent assay (ELISA).[Results]Overall, the prevalence of positive serum anti-HAV antibody was 92.78%, however, the rate for 15 - 24 years subjects was 69%. There was a significant positive correlation between presence of anti-HAV antibody with age (P < 0.001), marriage (P < 0.001), education (P = 0.001) and anti-Hbc antibodies (P = 0.007).[Conclusions]The result of this study showed a high prevalence of HAV antibody in most people, except for young adults, which can be an alarming sign for a higher rate of complicated HAV infections in the future and needs a proper strategy.
Journal title
Astroparticle Physics
Serial Year
2018
Record number
2411145
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