Author/Authors :
Mohebbi, Reza Research Institute of Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Sanati, Azar Research Institute of Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Cheraghipour, Kourosh Department of Parasitology - Lorestan Veterinary Office, Khorram Abad, IR Ira , Rostami Nejad, Mohammad Research Institute of Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Mohaghegh Shalmani, Hamid Research Institute of Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Zali, Mohammad Reza Research Institute of Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Abstract :
Background: There are little data on the prevalence of serological markers of hepatitis B and hepatitis C viruses in pregnant women in Iran.
Objectives: This study was designed to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection among pregnant women in Lorestan, west of Iran.
Patients and Methods: Serum samples of 827 pregnant women who lived in rural (36.8%) and urban areas (63.2%) of Lorestan were collected during 2007-2008. Data were obtained through questionnaires. Samples were first screened for anti-HCV and anti-HBc by ELISA. Those who were positive for anti-HBc were tested for HBsAg.
Results: Anti-HBc was found in 28 of 827 pregnant women (overall prevalence, 3.4%; 14 of 523 in urban areas, 2.7%; 14 of 304 in rural areas, 4.6%). Of the 28 positive samples, 6 (0.7%) were positive for HBs-Ag. Only 2 samples (0.2%) were anti-HCV-positive.
Conclusions: These results underscore the need for prenatal screening for HBV infection in pregnant women and treatment of newborns from HBsAg-positive mothers. More studies are needed to identify risk factors of HCV infection and highlight the importance of HCV screening and treatment programs.
Keywords :
Hepatitis B , Hepatitis C , Pregnant women , Anti-HBc antibody , HBs-Ag , Anti-HCV antibody