Author/Authors :
Ziabakhsh Tabary Shervin نويسنده , Mokhtari Esbuie Farzad نويسنده Mazandaran University of Medical Sciences, Sari, Iran. , Fazli Mehran نويسنده Faculty of Medicine, Student Research Committee, Mazandaran University of Medical Sciences, Sari, IR Iran
Abstract :
Abstract Background: Erectile dysfunction (ED) is common in cardiovascular
disease (CVD) and indicates a complication of coronary artery bypass graft
surgery (CABG). This study was designed to evaluate the status of erectile
dysfunction in patients with CAD before and after CABG surgery. Methods: We designed a prospective cohort study on male
patients candidates for elective on-pump CABG between June 2006 to October 2012
in 3 hospitals in Sari, Iran (Fatemeh Zahra, Shafa and Nime-Shaban Hospitals).
Patient’s primary data were collected based on the International Index of
Erectile Function questionnaire (IIEF-5) at baseline 6 months after surgery.
The severity of dysfunction was categorized as, normal, mild to moderate and moderate
to severe based on IIEF score. Results: Four hundred twenty-six male patients with mean age
of 58.69±12.49 years participated in this study. 166 patients had DM (38.96%)
230 patients had hypertension (54%). 307 patients had three-vessel impairment
(72.07%) and 119 patients with one or two vessel impairment (27.93%). The 15.02%, 18.07%, 23%,
31.92% and 11.97%, at baseline changed to 16.90%, 19.95%, 23.71%, 32.22% and
8.21%, at endpoint (P=0.01). Also, the mean±SD of IIEF-5 score
before and after surgery was 13.95±5.44 and 14.20±5.69, respectively (P=0.001). Conclusion: The result of
our study shows that on-pump CABG surgery has a positive effect on the improvement
of erectile dysfunction 6 months after surgery.
