Author/Authors :
Mohammadzadeh Iraj نويسنده , Alizadeh-Navaei Reza نويسنده Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran , Akbarian Rad Zahra نويسنده Babol University of Medical Sciences, Babol, IR
Iran , Haghshenas Mojaveri Mohsen نويسنده Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran. , Bouzari Zinat Al-Sadat نويسنده , Haddad Ghamar نويسنده
Abstract :
Abstract Background: Interleukin-6 (IL-6) has a major role in
hematopoiesis, immune and acute phase response and its serum level seems to be
associated with the mode of delivery. The purpose of this study was to compare
the level of IL-6 in mothers who delivered via cesarean section and vaginally. Methods: This cross-sectional study was done on 40 mothers
with vaginal delivery and 40 mothers with elective cesarean delivery in
2012 in Ayatollah Rouhani Teaching Hospital in Babol, northern Iran. Five ml
blood samples were taken from each mother. Blood samples were examined by enzyme-immune assay for the determination of IL-6 in
both mothers and neonates. Other information, such as the motherʹs age, newborn
sex, gravity, parity, the number of live births of each mother, and the status
of infants in terms of being term or pre-term, was recorded. Results: The mean age of cesarean section and vaginal delivery
patients was (29±5.01) yrs and (27.3± 4.93) yrs. The maternal IL-6
concentration in vaginal birth (170.13 ±15.9) was significantly (p<0.05(higher than cesarean section
(33±29.94) Conclusion: The result shows that serum IL-6 levels in patients
with vaginal delivery was higher than those with elective cesarean section
delivery. So, vaginal delivery is preferred for all patients except those in whom
vaginal delivery is contraindicated.
