Title of article :
Renal Actinomycosis, A Rare Diagnosis Which Can Clinically Mimic a Malignancy, Case Report and Review of the Literature
Author/Authors :
Nili Fatemeh نويسنده Dept. of Pathology, Tehran University of Medical Sciences, Tehran , Moradi Behnaz نويسنده Department of Radiology, Advanced Diagnostic and
Interventional Radiology Research Center (ADIR), Imam Khomeini
Hospital Complex, Tehran University of Medical Sciences, Tehran,
Iran , Niknejad Nakisa نويسنده Department of Anatomical and Clinical Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran , Niknezhad Nasim نويسنده Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Safaei Masoomeh نويسنده Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IR Iran
Abstract :
[Introduction]Actinomycosis is an unusual infection, which usually appears in the thoracic, cervicofacial, and abdominal areas. Renal actinomycosis is rare and has not yet been reported in children.[Case Presentation]An 8-year-old boy presented with a fever, weight loss, and flank pain two weeks after a sore throat. As the imaging studies were in favor of the malignant tumor of the right kidney, he underwent right radical nephrectomy. Pathologic study revealed Xanthogranulomatous pyelonephritis and actinomyces bacterial colonies.[Conclusion]Renal actinomycosis is difficult to diagnose due to its non-specific clinical findings and near similarity to other inflammatory and tumoral conditions. Early diagnosis is important for medical treatment and decrease of un-necessary surgery. Using auxiliary diagnostic methods can be helpful in this aspect. Percutaneous core needle biopsy or fine needle aspiration possesses higher accuracy and specificity in comparison with other methods.