Author/Authors :
Pakdaman Hossein نويسنده , Ashrafi Farzad نويسنده Department of Neurology, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Arab Ahmadi Mehran نويسنده Functional Neurosurgery Research Center, Shohada Tajrish Hospital,Shahid Beheshti University of Medical Sciences,Tehran,Iran , Behnam Behdad نويسنده Functional Neurosurgery Research Center, Shohada Tajrish Hospital,Shahid Beheshti University of Medical Sciences,tehran,iran , Mohamad Ali Shafa نويسنده Neurology Research Center, Kerman University of Medical Sciences, Kerman
Abstract :
Background and Purpose: The increased risk for cognitive defects in individuals affected bymetabolic syndrome especially in those patients with cardiovascular disorders is now claimed.We aimed to assess the relationship between cognitive performance and the various componentsof metabolic syndrome.Methods: One hundred and eighteen consecutive individuals aged 30 to 86 years were includedinto this cross-sectional survey. The metabolic syndrome and its definitive components weredefined according to the definition described in the Framingham Heart Study by NCEP ATP IIIcriteria. The Montreal Cognitive Assessment (MOCA) questionnaire was employed to cognitivescreening.Results: Those patients with metabolic syndrome had significantly lower mean MOCA scorecompare to the group without metabolic syndrome (19.11 ± 5.49 versus 21.28 ± 4.56, p =0.021). Among all cognition sub domains, the mean attention score was significantly lower inthe group with metabolic syndrome than in another group. In a multivariate linear regressionmodel adjusting sex and age variables showed that the presence of metabolic syndrome couldeffectively predict cognitive impairment (beta = -2.202, SE = -0.214, p = 0.013).Conclusion: The presence of metabolic syndrome can be mainly related to damaging cognitionespecially impairing the power of attention
