Author/Authors :
Hebrani Paria نويسنده , Ashrafzadeh Farah نويسنده , Sheikhani Ali نويسنده Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran , Sadeghi Bajestani Ghasem نويسنده Department of Biomedical Engineering, Science and Research
Branch, Islamic Azad University, Tehran, IR Iran , Hashemi Golpayegani Seyed Mohammad Reza نويسنده Amirkabir University of Technology
Abstract :
Asymmetry and symmetry coexist in natural and human processes, and the
interaction of asymmetric action (recursion) and symmetric opposition (sinusoidal waves)
is instrumental in generating creative features. Autism Spectrum Disorder (ASD) is a
disorder in which asymmetry and functionality of brain hemispheres are aected. In this
study, dierence in brain asymmetry in ASD and normal children and the eect of voice on
asymmetry are being investigated. Due to abnormal cortical voice processing in ASD, data
recording is done in two situations: animation with audio (V-A) for 5 minutes and watching
the animation with muted audio band (VwA). Two Indexes Divergence (D) and number of
Poincare section points further from threshold (HD) as new biomarkers are being extracted.
Hemispheric asymmetry in ASD children does not follow norm patterns, and H and HD
indexes conrm a disorder in hemisphereʹs functionality in all statistical tests which can be
globally unveiled with Poincare section and extracted information. Two remarkable features
of the presented method are: data recording protocol specialized for ASD children and new
practical time-series analysis for detecting episodic patterns (complexes) as hallmark of
ASD dynamic and arrangement as an empirical measure of nonrandom complexity. The
presented method could detect these complexes