Author/Authors :
biazar Esmaeil نويسنده Young Researchers Club – Tonekabon Branch , Heidari Keshel Saeed نويسنده Proteomics Research Center, Faculty of Paramedical Sciences , Zaeifi Davood نويسنده Proteomics Research center - Shahid Beheshti University of medical sciences , Ojani Sanaz نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University , Hajiaghaee Arefeh نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University , Safarpour Roya نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University , Sheikholeslami Mahkameh نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University , Heidari Banafsheh نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University , Sadeghpour Saba نويسنده Department of Biomaterials Engineering - Tonekabon Branch, Islamic Azad University
Abstract :
Poly vinyl alcohol/Chitosan nanofibrous mat were prepared by electrospinning method with suitable pore sizes as potential matrices for soft tissue engineering. The designed scaffolds by electrospinning method evaluated by differentanalyses such morphological, mechanical, and cellular analysis.Microscopic results showed diameters of poly vinyl alcohol/Chitosan nanofibers were approximately 150 nm. Mechanical investigations illustratedstress - strain curve of poly vinyl alcohol /chitosan mat indicate good flexibility with average strain and good percentage of yield stress. The cellular resultsrevealthat addition of chitosan to poly vinyl alcohol enhances viability and proliferationof fibroblast cells, which increases the biocompatibility of the scaffold. In fact, addition of a smallpercentage of chitosan to the poly vinyl alcoholproved to be a promising approach for designof a scaffold.
