Title of article :
Protective effects of accompanying proteins on light- and water-mediated degradation of Curcumin
Author/Authors :
Khodarahmi Reza نويسنده Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran , Ashrafi Kooshk Mohammad Reza نويسنده , Mirzaee Farideh نويسنده Medical Biology Research Center - Kermanshah University of Medical Sciences , Rezaei-Tavirani Mostafa نويسنده Proteomics Research Center - Faculty of Paramedical Sciences - Shahid-Beheshti University of Medical Sciences
Abstract :
Curcumin is a natural polyphenolic compound with anti-cancer, anti-inflammatory, and anti-oxidation properties. Low water solubility and rapid hydrolytic degradation are two challenges limiting use of curcumin as therapeutic agent. In the current study, the role of the Bovine Serum Albumin (BSA), B-lactoglobulin and casein, as food-grade biopolymers and safe drug delivery systems, on the physical activity of curcumin were surveyed. It appears that BSA and casein as protein vehicles are useful tools to increase stability of curcumin, as a health promoting agent.
Journal title :
Astroparticle Physics
