Hemodynamic Charactristics Comparing 2% Lidocaine With Epinephrine and Citanest 3% With Felypressin in Lower Third Molar Surgery

Introduction: Monitoring the patient’s status is necessary during the surgical extraction of teeth, especially when the procedure is traumatic or the patient has psychological problems. Stress induced by pain during dental treatments can result in the secretion of endogenous catecholamines which in turn increases hemodynamic changes. The present study aimed to compare hemodynamic changes after using lidocaine-epinephrine and prilocaine-felypressin during the third lower molar surgical extraction. Materials and Methods: In this prospective randomized clinical trial, 68 patients were selected and allocated into two groups. In group I, two cartridges containing 2% lidocaine, 1.8 mL and adrenaline 1.80000 were used. In group II, the subjects received two cartridges containing 3% prilocaine with 0.03 IU/ mL of felypressin. An anesthetic technique was used for the surgical extraction of teeth. For each subject, systolic and diastolic blood pressures, heart rate, and respiratory rate were measured three times. The mean of these three measurements were compared with that measured at the first visit of the patient. The obtained data were analyzed using SPSS V. 21. The Student t test was applied for comparisons. Results: Statistically significant differences were observed before and after using lidocaine-epinephrine in both sexes (P<0.0001) regarding the systolic blood pressure, diastolic blood pressure and pulse rate. Conclusion: The findings of the present study showed that the hemodynamic effects were not significantly different in patients receiving lidocaine with epinephrine and those receiving prilocaine with felypressin.