Title of article :
Parenteral Albumin Therapy in Burn Patients: A Randomized Controlled Trial
Author/Authors :
Mohammadi, Ali Akbar Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Hashemi-Nasab, Mohammad Jalal Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Ershadi, Reza Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Tavakkolian, Ahmad Reza Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Fakhar, Nasir Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Tolide-ie, Hamid Reza Shiraz Burn Research Center - Shiraz University of Medical Sciences - Shiraz , Mohammadi, Mohammad Kazem Faculty of Science - Islamic Azad University - Ahvaz Branch - Ahvaz
Abstract :
Background: Administration of albumin for burn patients and
its effects on mortality and morbidity has been debated for
along time. The aim of this study was to evaluate the effects of
albumin administration on wound healing, length of hospital
stay, weight change, and mortality of burn patients.
Methods: Two matched groups of patients from Shiraz Burn
Care Center were randomly selected. The patients in one
group received parenteral albumin in addition to high protein
diet and the other group received only high protein diet. The
length of hospital stay, healing time, mortality, serum albumin,
transferrin levels, and weight loss were compared.
Results: A total of 141 patients were selected; 71 patients in
control group and 70 patients in albumin group. There were no
significant differences in mortality (P=0.97), length of hospital
stay (P=0.45), and healing time (P=0.25) in two groups. The
patients who survived had significantly higher serum transferrin
level (128 mg/dL versus 102 mg/dL).
Conclusion: Parenteral albumin administration did not have a
significant effect on mortality, length of hospital stay, and
healing time in burn patients
Keywords :
Albumin , burn , transferrin , wound healing
Journal title :
Astroparticle Physics
