Title of article :
Effect of External Use of Sesame Oil in the Prevention of Chemotherapy-Induced Phlebitis
Author/Authors :
Nekuzad, Nilufar Faculty of Nursing and Midwifery - International Branch of Shahid Beheshti University of Medical Sciences, Tehran - Army University of Medical Sciences, Tehran , Ashke Torab, Tahereh Department of Nursing and Midwifery - Shahid Beheshti University of Medical Sciences, Tehran , Mojab, Faraz Pharmaceutical Sciences Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Alavi-Majd, Hamid Department of Biostatistics - Faculty of Paramedicines - Shahid Beheshti University of Medical Sciences, Tehran , Azadeh, Payam Department of Radiation Oncology - Imam Hossain Hospital - Shahid Beheshti Medical Sciences University, Tehran , Ehtejab, Gholamreza Departmen of Radiation Oncology - Beasat Hospital - Armey Medical Sciences University, Tehran
Pages :
7
From page :
1065
To page :
1071
Abstract :
Intravenous chemotherapy is an important mean for the treatment of cancers. Infusion phlebitis (Ph) is a common and acute complication of chemotherapy. The frequency of Ph is about 70% in patients undergoing chemotherapeutic management. It can induce the pain, increase the risk of thrombophlebitis, lead to incomplete follow-up, and thereby, affect the patient’s health status. Respecting the great importance of these issues, it is essential to prevent Ph. This study conducted to determine the effect of external use of Sesame Oil (SO) in the prevention of Ph. Sixty patients with colon or rectum cancer, who admitted for chemotherapeutic management, enrolled in clinical trial and were randomly divided into two equal groups: Control and Intervention. Ten drops of SO was applied twice a day for 14 days externally in intervention group, whereas the control group received nothing. Incidence and grade of Ph was measured in both groups. Data was analyzed through independent t-test, Χ2, Fisher’s exact test, Mann-Whitney, and Lagrange survival using SPSS 16. The incidence of Ph was 10% and 80% in intervention group and control group, respectively.There was a significant difference between two groups (p < 0.05). Ph was 8 times more frequent in control group (R R = 8; AR R = 70%). In addition, there was statistically significant difference between the grade and incidence of Ph with SO and control group (p < 0.05). According to these results, it seems that external use of SO is effective, safe and well-tolerated for prophylaxis from Ph. Therefore, it can be suggested as a selected prevention method for reducing the complication.
Keywords :
Sesame Oil , Prophylaxis , Phlebitis , Chemotherapy
Journal title :
Astroparticle Physics
Serial Year :
2012
Record number :
2414849
Link To Document :
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