Title of article :
Effects of Siraitia grosvenorii Fruits Extracts on Physical Fatigue in Mice
Author/Authors :
Liu, Da-Duo Physical Education Institute of Jilin Normal University - Siping City - Jilin 136000, China , Ji, Xue-Wu Physical Education Institute of Jilin Normal University - Siping City - Jilin 136000, China , Li, Rong-Wei Department of Physical Education of Hebei Normal University of Science and Technology - Qinhuangdao City - Hebei 066004, China
Abstract :
In this study, the effects of Siraitia grosvenorii fruits extracts (SGFE) on physical fatigue were investigated. One hundred and forty-four mice were randomly divided into four groups: control group, low-dose SGE-treated group, middle-dose SGE-treated group and highdose SGFE-treated group. The animals of control group received an oral administration of physiological saline in a volume of 2.5 mL, and the animals of treated group received the same volume of SGFE (100, 200 and 400 mg/Kg bodyweight, once a day) for 28 days. After 28 days, anti-fatigue effects of SGFE were assessed 10 h after the last treatment by forced swimming test and some biochemical parameters related to fatigue, including blood lactic acid, serum urea nitrogen, liver glycogen and muscle glycogen were measured. The data showed that SGFE can extend the swimming time of the mice, as well as increasing the liver and muscle
glycogen contents, but decrease the blood lactic acid and serum urea nitrogen levels. These results indicated that Siraitia grosvenorii fruits extracts had significant anti-fatigue effects on mice and these effects were dose-dependent.
Keywords :
Siraitia grosvenorii fruits extracts , Physical fatigue , Mice , Forced swimming test
Journal title :
Astroparticle Physics