Title of article :
Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
Author/Authors :
Moghbel, Abdolhossein Department of Pharmaceutics - School of Pharmacy - Ahvaz Jundishapur University of Medical Sciences, Ahvaz , Abbaspour, Hamideh Department of Clinical Pharmacy - School of Pharmacy - Shahid Beheshti University of Medial Sciences, Tehran
Pages :
7
From page :
231
To page :
237
Abstract :
The aim of the present study was to prepare an oral tablet from liquid yogurt by reforming the physical properties for easy transportation, long-term storage and also as a complementary dairy product in case of nutrient deficiency. The liquid fresh yogurt was lyophilized at -40°C and 0.03 mTor pressure. The dry powder was homogenized by a 12 mesh size sieve. Some tests such as Carr’s compressibility index, Hausner ratio and the angle of repose were applied to evaluate the flowability of yogurt powder. Study of the deformation of particles during forcing was done by calculation of the elastic recovery index. Carr’s compressibility index percent and Hausner ratio were calculated 15 and 0.94, respectively. The range of repose angle was measured between19-20°. The elastic recovery was obtained up to 60%. Since the hardness of tablets increased by decreasing compression velocity, therefore yogurt powder might have a plastic deformation. The reduction of powder volume due to compression force was about 20% (p < 0.05). Tablets with low fat yogurt showed very good compressibility with 6-12 Strong-Cab (SC) hardness units. Producing a complementary formulated as a tablet from yogurt powder is possible and also maybe therapeutically effective against lactoseintolerance syndrome and preventing antibiotic-associated diarrhea.We suggest that for more authentic confirmation of the type of deformation, it should go through Heckel’s equation analysis, too.
Keywords :
Yogurt , Compressibility , Plastic deformation , Tablet processing , Dietary supplements , Lyophilization
Journal title :
Astroparticle Physics
Serial Year :
2013
Record number :
2414968
Link To Document :
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