Author/Authors :
Nazari, Hossein Eye Research Center - Iran University of Medical Sciences, Tehran, Iran , Modarres-Zadeh, Mehdi Eye Research Center - Iran University of Medical Sciences, Tehran, Iran , Maleki, Arash Eye Research Center - Iran University of Medical Sciences, Tehran, Iran
Abstract :
The vitreoretinal interface is involved in a wide range of vitreoretinal disorders and
separation of the posterior vitreous face from the retinal surface is an essential part
of vitrectomy surgeries. A diverse range of enzymatic and non-enzymatic agents are
being studied as an adjunct before or during vitrectomy to facilitate the induction of
posterior vitreous detachment. There is a significant body of knowledge in the literature
about different vitreolytic agents under investigation for a variety of pathologies
involving the vitreoretinal interface which will be summarized in this review.