Author/Authors :
Ostadimoghaddam, Hadi Refractive Error Research Center - School of Paramedical Sciences - Mashhad University of Medical Sciences, Mashhad, Iran , Yekta, Abbas Ali Refractive Error Research Center - School of Paramedical Sciences - Mashhad University of Medical Sciences, Mashhad, Iran , Heravian, Javad Refractive Error Research Center - School of Paramedical Sciences - Mashhad University of Medical Sciences, Mashhad, Iran , Fotouhi, Akbar Department of Epidemiology and Biostatistics - School of Public Health - Tehran University of Medical Sciences, Tehran, Iran , Hashemi, Hassan Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Abdolahinia, Tahereh Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Norouzi Rad, Reza Dezful University of Medical Sciences, Dezful, Iran , Asgari, Soheila Noor Ophthalmology Research Center - Noor Eye Hospital, Tehran, Iran , Khabazkhoob, Mehdi Department of Epidemiology - Faculty of Public Health - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Purpose: To determine the range of contrast sensitivity (CS) and its determinants in a
normal population, Mashhad, Iran.
Methods: In this cross-sectional population based study, 4,453 individuals were invited
of whom 3,132 persons agreed to participate (response rate, 70.4%). CS data from
2,449 eligible individuals were analyzed. CS was determined using the Cambridge low
contrast square-wave grating test, and its associations with age, gender, best-corrected visual acuity (BCVA) and manifest refraction spherical equivalent (MRSE) refractive error, were analyzed.
Results: Mean age of the participants was 29.1±17.3 (range, 4–89) years and 66.4% were female. Mean CS was 239.6±233.3 and 234.6±228.6 cps in right and left eyes, respectively. Mean binocular CS was 310.9±249.0 cps. Multiple linear regression showed that CS was inversely correlated with older age (β=-1.1, P<0.001), female gender (β=-40.1, P<0.001), poorer BCVA (β=-165.4, P<0.001), and severity of myopia (β=-10.2, P<0.001). Conclusion: The normal range of Cambridge low-contrast grating test reported herein may serve as a reference for the general population in Iran. Our findings can be used for both research and clinical applications, particularly for evaluations of the outcomes of refractive surgery. In the current study, CS was lower in older subjects, myopic individuals and patients with lower BCVA.
Keywords :
Normal Value , Contrast Sensitivity , Cambridge Test , Population Based Study