Author/Authors :
Moradkhani, Shirin Department of Pharmacognosy and Biotechnology - School of Pharmacy - Hamadan University of Medical Sciences, Hamadan , Kobarfard, Farzad Department of Medicinal Chemistry - School of Pharmacy - Shahid Beheshti University of Medical Sciences, Tehran - Phytochemistry Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Ayatollahi, Abdol Majid Phytochemistry Research Center - Shahid Beheshti University of Medical Sciences, Tehran - Department of Pharmacognosy and Biotechnolgy - School of Pharmacy - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after
fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done.
Keywords :
Achillea tenuifolia , Asteraceae , Eupatorine , Lupeol , Daucosterol
