Title of article
Risk Factors of Glucocorticoid-Induced Diabetes Mellitus in Systemic Lupus Erythematosus
Author/Authors
Zabihi Yeganeh, Mojdeh Department of Internal medicine - Firoozgar Hospital - Iran University of Medical sciences, Tehran , Sadeghi, Saeideh Department of Internal medicine - Firoozgar Hospital - Iran University of Medical sciences, Tehran
Pages
5
From page
39
To page
43
Abstract
Background: The aim of this study was to investigate the prevalence and associated factors of glucocorticoid-induced Diabetes mellitus (GIDM) in patients with systemic lupus erythematosus (SLE) under glucocorticoid therapy.Martials and Methods: Patients with SLE who had received high-dose glucocorticoid therapy (prednisolone≥1 mg/kg/day) at Rasoul Akram and Firoozgar hospitals were recruited during 2006-2011.Results: A total of 81 patients with SLE were evaluated. 21 patients (25.9%) of them developed GIDM after high-dose glucocorticoid therapy. Univariate analysis of data showed that old age, family history of diabetes mellitus (DM) and use of Mycophenolate mofetil were factors that would increase the likelihood of GIDM.Conclusion: In summary, GIDM was developed among 25.9% of patients with SLE after high-dose glucocorticoid therapy. Old age, family history of DM and use of Mycophenolate mofetil were determ ined to be factors responsible for increasing the risk of developing GIDM.
Keywords
Diabetes Mellitus , Glucocorticoid , Systemic Lupus Erythematosus , Risk factor
Journal title
Astroparticle Physics
Serial Year
2013
Record number
2417819
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