Author/Authors :
Rahmani, Hojjat Department of Health Management and Economics - School of Public Health - Tehran University of Medical Sciences, Tehran, Iran , Sarabi Asiabar, Ali Health Management and Economics Center - Iran University of Medical Sciences, Tehran, Iran , Niakan, Somayeh Department of Prosthodontics - School of Dentistry - Tehran University of Medical Sciences, Tehran, Iran , Hashemi, Yaser Fasa University of Medical Sciences, Fasa, Iran , Faramarzi, Ahmad Department of Public Health - School of Health - Urmia University of Medical Sciences, Urmia, Iran , Manuchehri, Sahar Department of Health Management and Economics - School of Public Health - Tehran University of Medical Sciences, Tehran, Iran , Rajabi Vasokolaei, Ghasem Department of Health Management and Economics - School of Public Health - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Background: Iran is located in Asian esophageal cancer belt, with age-standardized incidence rate (ASR) of approximately 7 per
100,000 for both men and women. To provide potential solution recommendations for achieving accurate estimations regarding the
burden of the disease in Iran, we designed a study to assess the burden of esophageal cancer in Iran during 1995-2015 by collecting
data from the Global Burden of Disease studies.
Methods: Data were extracted from the Global Burden of Disease (GBD) during 1995-2015, which were published by the Institute
for Health Metrics and Evaluation. For this purpose, disability adjusted life years (DALYs), incidence, and prevalence rate were applied
to report burden of esophageal cancer based on gender and age group in Iran during 1995-2015. The Cochran-Armitage and t test
were used to assess statistical significance. Stata Version 13 and Excel 2016 were used for data analysis.
Results: During 1995-2015, in total, 304 102 DALYs (179 562 for males vs. 124 540 for females) were attributed to esophageal
cancer in Iran. In both genders and all ages, the number of DALYs increased significantly from 45 018 in 1995 to 74 399 in 2015.
Conclusion: Esophageal cancer is still a public health issue in Iran. Most of DALYs were due to years of life lost (YLL), suggesting
the need for prevention, early detection, and screening programs. P-value was statistically significant just between male and female
groups (p<0.05).
Keywords :
Global burden of disease , Disability adjusted life years , Esophageal cancer , Iran