Author/Authors :
Rakhee, Sodhi Department of Pulmonary Medicine - Himalayan Institute of Medical Sciences, Dehradun, Indian , Sushant, Khanduri Department of Critical Care Medicine - Himalayan Insitute of Medical Sciences, Dehradu, Indian , Varuna, Jethani Department of Pulmonary Medicine - Himalayan Institute of Medical Sciences, Dehradun, Indian , Nadia, Shirazi Department of Pathology - Himalayan Institute of Medical Sciences, Dehradun, India , Manoj, Kumar Department of Pulmonary Medicine - Himalayan Institute of Medical Sciences, Dehradun, Indian
Abstract :
The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN).
The antinuclear (ANA) and anti-neutrophil cytoplasmic antibodies (ANCA) are considered as relatively specific markers of the disease. Herein, we presented the case of a patient who initially presented with sepsis but did not respond to the conventional antibiotics and later diagnosed with GPA.
Keywords :
Antinuclear antibody , Anti-neutrophil cytoplasmic antibody , Granulomatosis With Polyangiitis , Sepsis
