Title of article :
Highly Sensitive Amperometric Detection of Propranolol using Graphite Screen Printed Electrode Modified with Zirconium Dioxide Nanoparticles
Author/Authors :
Mohammadizadeh, Nosrat Department of Chemistry - University of Sistan and Baluchestan , Mohammadi, Zia Department of Chemistry - Payame Noor University , Kaykhaii, Massoud Department of Chemistry - University of Sistan and Baluchestan
Abstract :
A graphite screen printed electrode modified with ZrO2 nanoparticles (ZrO2/SPE) was investigated for its ability to serve as a sensor towards propranolol. The ZrO2/SPE was found to exhibit an electro-catalytic activity for the electrochemical oxidation of propranolol in 0.1 M phosphate buffer solution (pH 7.0). Cyclic voltammetry and differential pulse voltammetry were employed to study the electrochemical properties of the modified electrode. The electrochemical oxidation of propranolol occurs at +0.95 V with a limit of detection (3σ) found to be 1.5 μM and with linear range of 10.0 μM to 200.0 μM. The present study widens the scope of applications of ZrO2 nanoparticles for on-site monitoring of propranolol.
Keywords :
Propranolol , ZrO2 nanoparticles , Graphite screen printed electrode , Voltammetry
Journal title :
Astroparticle Physics