Application of Glassy Carbon Electrode Modified with Co3O4 Nanoparticles for Voltammetric Determination of Folic Acid

Folate is another form of folic acid, which is known as one of the B vitamins. It is utilized as an additive by women during pregnancy in order to prevent the neural tube defects. The present study reports on the fabrication of electrochemical sensor for the determination of folic acid using Co3O4 nanoparticles. The suitability of Co3O4 nanoparticles as a modifier for the electrocatalytic detection of folic acid in aqueous solution was investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) techniques. The fabricated Co3O4 NPs/GCE sensor exhibited sharp and intense peak towards the electro-oxidation of folic acid as compared to bare electrode. The linear calibration plot of folic acid was obtained from 1.0 to 900.0 μM with the detection limit of 0.8 μM. The modified electrode was use for the detection of folic acid in real samples and found to produce satisfactory results.