Author/Authors :
Nikpour, Fatemeh Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , Vatandoost, Hassan Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , Hanafi-Bojd, Ahmad Ali Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , Raeisi, Ahmad Malaria Control Department - Ministry of Health and Medical Education, Tehran, Iran , Ranjbar, Mansour Independent Malaria Consultant, Tehran, Iran , Enayati, Ahmad Ali Department of Medical Entomology and Vector Control - School of Public Health - Mazandaran University of Medical Sciences, Sari, Iran , Abai, Mohammad Reza Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , Shayeghi, Mansoreh Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , Mojahedi, Abdol Rasoul Provincial Health Center - Bandar Abbas University of Medical Sciences, Bandar Abbas, Iran , Pourreza, Abolghasem Department of Medical Entomology and Vector Control - School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Background: The aim of this study was to evaluate different concentrations of deltamethrin combined with formu-lated piperonyl butoxide (PBO) synergist on various surfaces against the wild strain of Anopheles stephensi, the main malaria vector in Southern Iran under semi-field condition.
Methods: Four concentrations of deltamethrin WG 25% (Tagros) and PBO 800EC-UV (Endura) were prepared and sprayed on the pre-designed surfaces in accordance with WHO alliance line of the IRS Micronair®. The WHO’s rec-ommended bioassay kit and method was used during this study.
Results: Comparing the mortality rate of mosquitoes, the results showed a significant difference between months after treatment of IRS (Indoor Residual Spraying) (P< 0.05) but didn’t show any significant differences between days during the first and second months (P> 0.05).
Statistical test revealed a significance difference between mortality rate of mosquitoes in exposing to concentrations of 1 and 4 (P< 0.05) which demonstrated effect of synergizing PBO on mortality rate.
Conclusion: This research as the first semi-field trial on deltamethrin added to different concentrations of formulat-ed PBO for IRS, indicates that deltamethrin+10X PBO is more effective than other concentrations. Therefore, using synergists can be suggested as a new tool for prevention of pyrethriod resistance, although more studies are recom-mended.
Keywords :
Insecticide resistance , Anopheles stephensi , Deltamethrin , Piperonyl butoxide , IRS
