Author/Authors :
SHI, Jiana Dept. of Pharmacy - Tongde Hospital of Zhejiang Province, Hangzhou, China , WANG, Xiaojun Dept. of Pharmacy - Tongde Hospital of Zhejiang Province, Hangzhou, China , YING, Yin Dept. of Pharmacy - Tongde Hospital of Zhejiang Province, Hangzhou, China , XU, Lin Dept. of Cardiovascular Medicine - Tongde Hospital of Zhejiang Province, Hangzhou, China , Zhu, Danyan Dept. of Pharmacology - Toxicology and Biochemical Pharmaceutics - Zhejiang University, Hangzhou, China
Abstract :
Mirtazapine is a new antidepressant that can increase noradrenergic and serotonergic neurotransmission. It is also a postsynaptic antagonist of 5-HT2 and 5-HT3. In addition, it has only a weak affinity for 5-HT1 receptors and has very weak muscarinic anticholinergic and histamine (H1) antagonist properties. We report a case of hypertensive urgency that ensued after a patient took a single low dose of mirtazapine.
