Comparative Study of Antibacterial Activity of Nanosilver Synthesized Using Trigonosciadium brachytaenium (Boiss.) Alava Leaves Extract, Alone and Mixed with Gentamicin

Background: The phytosynthesis of Ag nanoparticles (AgNPs) by plant materials is emerging as an important branch of nanobiotechnology due to its eco-friendly, safe, and cost-effective nature. It also does not produce any noxious materials. Objectives: Nanophytosynthesis of AgNPs by the Trigonosciadium brachytaenium leaf extract and the investigation of its antimicrobial activity and physicochemical properties are reported. Methods: AgNPs were prepared by a nanophytosynthesis method. The structural and properties of the NPs were investigated by spectroscopy. The antimicrobial effect against seven bacterial species was studied according to the agar diffusion cup method. Results: The bioassay showed that the silver nanoparticles exhibited a good antimicrobial activity. The average particle size was found to be 32 - 33 nm. Conclusions: This study demonstrated the possible use of phytosynthesized AgNPs in the field of medicine. The approach of AgNPs phytofabrication with T. brachytaenium emerges to be very effective as an alternative to the common procedures of fabrication.