Author/Authors :
KAEWPITOON, Natthawut Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , KAEWPITOON, Soraya Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , MEERERKSOM, Thirayu Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , CHAN-ARAN, Siwawich Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , SANGWALEE, Wararat Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , NORKAEW, Jun Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , CHUATANAM, Jirayu Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , KUJAPAN, Jirawoot Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Roi-Et, Thailand , PADCHASUWAN, Natnapa Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Khon Kaen, Thailand , TONGTAWEE, Taweesak Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , MATRAKOOL, Likit Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , LOYD, Ryan Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand , WAKKHUWATTHAPONG, Parichart Parasitic Disease Research Center - School of Medicine - Suranaree University of Technology, Nakhon Ratchasima, Thailand
Abstract :
Background: Opisthorchis viverrini is a serious health problem in Southeast Asia. The infection is
associated with cholangiocarcinoma. Therefore, this study was aimed to detect O. viverrini infections
among the ASEAN population in Thailand.
Methods: A cross-sectional study was conducted among 249 individuals from ASEAN populations
in Thailand including Thai, Laotian, Cambodian, and Myanmar. Participants were screened
using the O. viverrini verbal screening test (OvVST). Fecal samples were processed by the miniparasep
sf parasite fecal concentrator.
Results: The infection rate of O. viverrini was 27.21%. The majority of infections was detected in
females, in the age group 31-40 yr old, in the primary school education level, and in the occupation
of labor. By country, O. viverrini infection was detected more often in the Lao PDR (30.77%). In
screening for O. viverrini infection, OvVST had a high sensitivity (93.48%), specificity (86.70%),
NPV (98.32%), and accuracy (87.95%). The PPV was 61.43% for OvVTS. The observed agreement
was substantial for OvVST (k-value = 0.64).
Conclusion: O. viverrini infections are still detected in ASEAN countries therefore large scale active
surveillance is required. OvVST had a high sensitivity, specificity, and accuracy for screening the
risk groups for O. viverrini.
