Author/Authors :
Molla Mohammadi, M. Pediatric Neurology Research Center - Qom University of Medical Sciences, Qom, Iran , Karimzadeh, P. Pediatric Neurol ogy Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Khatami, A. Department of Radiology - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Jadali, F. Department of Pediatric Pathology - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Ataxia is a movement disorder that may manifest an acute, intermittent, non progressive or
chronic progressive course. Ataxia alone is rare as a paraneoplastic sign, especially if it is due to
neuroblastoma (abdominal or chest).
We report an abdominal neuroblastoma in a two-year-old girl presenting with only acute ataxia
and abnormal neuroimaging. Brain MRI showed abnormal signal finding in the medulla, pons,
corticospinal tract and the periventricular space. In the abdominal CT, a mass was detected
in the right adrenal gland with calcification and the histopathologic examination re-vealed
neuroblastoma.
We suggest in children with acute ataxia, with or without opsoclonus-myoclonus, neuroblastoma
should be considered.