Author/Authors :
Nourbala, Mohammad Hossein Nephrology and Urology Research Center - Baqyiatallah University of Medical Sciences, Tehran, Iran , Nemati, Eqlim Nephrology and Urology Research Center - Baqyiatallah University of Medical Sciences, Tehran, Iran , Azizabadi Farahani, Mehdi Clinical Research Unit - Baqyiatallah University of Medical Sciences, Tehran, Iran , Kardavani, Babak Medicine and Health Promotion Institute, Tehran, Iran , Namdari, Mahshid Medicine and Health Promotion Institute, Tehran, Iran , Khoddami Vishteh, Hamidreza Medicine and Health Promotion Institute, Tehran, Iran , Moghani Lankarani, Maryam Tehran Medical Branch - Islamic Azad University, Tehran, Iran
Abstract :
Introduction. Undergoing transplantation is extremely stressful,
and a recipient is likely leave the hospital burdened with fears
of an uncertain future. A paucity of knowledge on the long-term
survival of rehospitalized kidney transplant recipients is the likely
the reason that physicians fail to provide this group of patients
with promising information and reassurance about their future.
We sought to describe the long-term patient and graft survival
after nonfatal rehospitalization in kidney recipients with a normal
graft function after discharge.
Materials and Methods. We reviewed the follow-up data (from
the time of discharge after first rehospitalization) of 253 kidney
transplant recipients who had been discharged from rehospitalization
with a normal kidney function (serum creatinine less than 1.6 mg/
dL). Patient and graft survival rates 6 months and 1, 2, and 5 years
after discharge were determined.
Results. The mean duration of follow-up (from the time of discharge
after the first rehospitalization) was 38.9 ± 11.2 months (range, 6 to
84 months). The overall patient survival rates were 98%, 97%, 95%,
and 93% at 6 months, 1 year, 2 years, and 5 years, respectively.
Graft survival rates at these times were 88%, 82%, 77%, and 63%,
respectively. After the first posttransplant rehospitalization, 54
patients (21.9%) experienced more hospitalization episodes (mean,
2.6± 2.0 times), while 193 (78.1%) had no further hospitalizations
during the follow-up period.
Conclusion. Kidney transplant recipients who are rehospitalized
should be reassured about favorable chances of survival if discharged
with a normal graft function.